African Journal of Biological Sciences




Dr. Eugene A. Silow









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Current Issue of African Journal of Biological Sciences

Volume 6, Issue 1, January 2024
Research Article

Molecular and immunological study of hepatitis viral in children in Ramadi City | Open Access

Ghaith M. Ahmad, Noor Naji Al-Hayani , Ammar M. Abdulla, Safaa A. Al-Waysi

Afr.J.Bio.Sc. 6(1) (2024) 110-120 DOI: 10.33472/AFJBS.6.1.2024.110-120
Received: 17/11/2023|Accepted: 08/12/2023|Published: 05/01/2024


Background: The worldwide prevalence of Viral Hepatitis has been the cause of severe liver diseases and cancers, affecting more than 300 million people. As for the AL-Anbar region in Iraq, this study sheds light on the prevalence rate among children of hepatitis with its three classifications: A, B, and C. Materials and Methods: A retrospective analysis of 127 children aged 6 months to 15 years was performed. Comprehensive diagnostic techniques were utilized on collected blood samples, including biochemical and rapid tests (IgM and IgG detection), ELISA, and rtPCR. Results: Analysis, carried out using IBM SPSS (Statistical Package for the Social Sciences) software, unveiled that Hepatitis A was the predominant infection (39.4%), succeeded by Hepatitis B (33.1%), and Hepatitis C (27.6%). A notable correlation was observed between ELISA and PCR test outcomes for all three types of Hepatitis, reinforcing the efficacy of these diagnostic methods. Conclusion: The substantial prevalence of hepatitis types A, B, and C in the AL-Anbar children's community mandates prompt public health interventions. Emphasizing the need for effective screening, our study highlights the necessity for implementing preventive strategies to curb the spread of these infections.

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