Acne vulgaris is a common cutaneous inflammatory disorder of the pilosebaceous unit, which runs a chronic course. A scar (also named cicatrix) is a skin lesion that results from the healing of wounds due to chemical, mechanical, or thermal injuries. Scars can develop after skin inflammation, for example, as a complication of acne. Scar formation is part of the wound healing process, which is divided into three phases: inflammatory, healing, and remodeling. The inflammatory phase begins in the first 6 h after the skin is injured and continues for the next 48–72 h. During this phase, blood vessels dilate, and their permeability increases under the influence of kinins, histamine, prostaglandins, and leukotrienes. The skin is visibly swollen and red. Acne scar, one of the most persistent complications of acne, causes distress to the appearance and psychology of the patient.