Anabolic-androgenic steroids (AASs) are testosterone analogues that have both anabolic and androgenic functions. They are used to treat variety of serious pharmaceutical conditions such as renal diseases, blood disorders, delayed puberty in men, hereditary edema, osteoporosis and growth deficiency. The prostate is the largest accessory gland in the reproductive system of male. It secretes a slightly alkaline fluid that appears to form about one third of the seminal fluid in human. The development and function of the prostate is dependent on androgens produced mainly in the testes. Anabolic androgenic steroids (AASs) users are typically in their late 20 years old to early 30 years old and most often are heterosexual males although gay/bisexual men presented extensively in the anabolic androgenic steroid community. The main reasons for administrating AASs are to increase strength and muscle mass. The majority of AAS abusers is non-competitive and appears to be driven mostly by personal goals such as achieving a more ideal body, raising performance levels, or boosting confidence. AASs are typically used in phases referred to as cycles: ‘on cycles’ means specific periods when the users administer AASs and ‘off cycles’ means an AASs -free phase. During ‘on cycles’ users sometimes combine different injectable and oral AASs.