A wide variety of mixed metal ligand complexes and their composites were studied by many researchers and discussed about their use in the medicinal chemistry, making of ferroelectric devices, piezoelectric transducers, magnetic sensors, and dielectric materials. The extensive literature survey carried out by us revealed that not much work has been done on studies related to use of various combinations of mixed metal-ligand complexes for antimicrobial applications. The present study deals with the synthesis, characterization, and evaluation of antimicrobial activity study of Strontium Tartrate complexes, which contain R=Sr (fixed metal ion) with R=Zn, Cu, Co, Mn (transition metal ions) bonded together by dentate tartrate ligands. The Strontium Tartrate Complexes were synthesized by a simple co-precipitation method and then purified. The said complexes were characterized using X-ray diffraction, UV visible, IR and Raman spectroscopy. The XRD analysis showed that the complexes are having polycrystalline nature. The UV visible spectroscopy showed that the Strontium Zinc and Strontium Cobalt tartrate complexes have very high UV absorption in certain windows and therefore they can be used in design and development of UV filters. The IR analysis in consistent with Raman analysis showed stretching of C-H, C-O, C=C and C≡C bonds representative sp2 and sp3 hybridized carbon atoms. The anti-microbial activity of all the four complexes have been studied with S. Aureus and E. Coli bacteria and the results showed that S. Aureus bacteria is more sensitive to the complexes than E. coli. By and large the Strontium tartrate complexes have shown their ability to be used in formulating drugs against bacteria. Details are presented.