Background: Life skills and emotional security have a key role in shaping a child's development, Aim of the study: Assess life skills and emotional security among preschool children. Subjects and Methods: Cross-sectional descriptive design was conducted in four governmental nursery schools in Zagazig City on 220 preschool children. The data were collected using an interview questionnaire with two standardized scales namely the life skills scale, and the emotional security scale. Results: Children’s mean age was 5.30, 53.6% were males. About 57.7% of the children had high life skills and 84.5% had high total emotional security. Significant positive correlations were revealed between life skills and emotional security (r=0.336). In multivariate analysis, emotional security was positive predictors of life skills scores. Conclusion and Recommendations: The results of the study lead to the conclusion that life skills are better although still low in about half of the preschool children. Conversely, emotional security is mostly high except for the mood state. The study recommended that health education program for parents of preschool children regarding improving life skills and emotional security, training program for parents and their children focus on improving life skills and emotional security and further studies are proposed to investigate the factors affecting life skills and emotional security of preschool children.