Backround. Human resources (HR) is one of the most important factors both in both companies and institutions. It determines the growth of a company. A corporation can increase its growth tremendously if it has many competent human resources for each department. To foster employees that are competent and professional at their jobs, effective management is necessary to increase the company's financial resources. Aims/Objective. The aim of this study was to analyze how leadership style and remuneration system affect the individual performance at the Regional General Hospital dr. TC. Hillers Maumere with motivation as an intervening variable. Methods. This study used survey research method, with an explanatory causality approach. Results. Results showed that employee performance will remain at 19.873 percent if the variables in this research—leadership style, work motivation, and remuneration system—are assumed to be equal to zero. There is an influence of leadership (p=0.000; B=0.306), motivation (p=0.000; B=0.057), remuneration (p=0.000; B=0.249) on employee performance. Furthermore, there is an influence of leadership (p=0.000; B=0.306) and remuneration (p=0.000; B=0.363) on on employee motivation. Conclusion. The hospital is expected to further improve the forms and models of motivation and compensation offered to its employees in order to maintain the quality of their performance.