Parkinson's disease (PD), a neurodegenerative disorder characterized by progressive motor impairments and non-motor symptoms, significantly impacts quality of life. While currently no cure exists, considerable evidence highlights the potential of exercise as a crucial non-pharmacological intervention to mitigate disease progression and enhance patient well-being. This abstract explores the multifaceted role of exercise in managing PD, encompassing its impact on motor and non-motor symptoms, underlying mechanisms, and future research directions. Exercise interventions, including aerobic, resistance, and balance training, demonstrably improve motor function in PD patients. Aerobic exercise, such as walking, cycling, and swimming, enhances cardiorespiratory fitness, improves gait, and reduces rigidity and bradykinesia. Resistance training strengthens muscles, combating weakness and improving activities of daily living (ADLs). Balance training, crucial given the increased fall risk in PD, enhances postural stability and reduces the incidence of falls. These motor improvements translate to increased independence, participation in social activities, and improved overall quality of life. Beyond motor benefits, exercise exerts positive effects on various non-motor symptoms. Studies suggest exercise can alleviate depression, anxiety, sleep disturbances, and cognitive decline, prevalent comorbidities in PD. The mechanisms underlying these benefits are multifactorial, involving neuroprotective effects, increased brain-derived neurotrophic factor (BDNF) levels, improved neuroplasticity, and modulation of neurotransmitter systems, particularly dopamine. Furthermore, exercise may influence inflammation, oxidative stress, and mitochondrial function, all implicated in PD pathogenesis. However, despite the promising evidence, several challenges remain. Optimizing exercise prescription, considering individual disease severity and comorbidities, is crucial. Standardized protocols and outcome measures are necessary for robust clinical trials to establish efficacy across different exercise modalities. Future research should focus on identifying optimal exercise types, intensities, durations, and frequencies for various PD stages and phenotypes, employing advanced neuroimaging techniques to elucidate the underlying neural mechanisms. Ultimately, integrating exercise into comprehensive PD management strategies is likely to significantly enhance patients' functional abilities, reduce disability, and improve their overall well-being.