Introduction: Efforts have been focused on wound management in order to develop novel healing and therapeutic techniques after tooth extraction. Calcium carbonate, which is also present inside the shells, makes up 95–99% of the bulk of blood clams. Previous research has shown that hydroxyapatite and tricalcium phosphate, which are useful in a variety of dental specialties, may be shaped from blood clam shells. Green clam shells contain about 95% CaCO3 and include mineral components that are similar to those found in bones, making them suitable for biomedical uses. research targets: examine the efficacy of green and blood clam shells as a material to quicken publish-extraction wound recovery in rats (Rattus norvegicus) used in experiments. methods: This study used a systematic review methodology. References have been accumulated from internet databases over the last 5 years, including portals for Pubmed, science Direct, Cochrane, and Wiley internet Library. A aggregate of blood clam (Anadara granosa) and green mussel (Perna viridis) shell extracts had been used to hurry wound healing after enamel extraction, according to journal papers that served as the basis for this systematic review. results: A total of 275 journals, acquired from four sources and obtained in accordance with the inclusion standards. As many as 6 decided on journals and data synthesis changed into completed. discussion: By analyzing the regeneration of alveolar bone and surrounding tissue, blood clam shells and green mussel shells have been shown to be efficient as materials that could hasten the healing of post-extraction wounds. conclusion: Blood clam and green mussel shells have been processed to provide hydroxyapatite as a uncooked material, and this substance has been successfully used to hasten the healing of wounds that have passed through extraction.